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Escaline fumarate

Escaline fumarate properties

Synonym: 3,5-dimethoxy-4-ethoxyphenethylamine fumarate
CAS Number: 39201-82-6
Formula: 2-{3,5-dimethoxy-4-ethyloxyphenyl}ethan-1-amine fumarate
Molar mass: 341.4 g/mol
Purity: >97%

Price range: €30.00 through €440.00

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* The information on this page is a summary and is not intended to cover all available information about this medication. It does not cover all possible uses, directions, precautions, drug interactions or adverse effects and is not a substitute for the expertise and judgment of your healthcare professional.

Escaline Fumarate – Innovative Psychedelic Phenethylamine for Scientific Research

Product name: Escaline Fumarate
Full Name: 3,5-dimethoxy-4-ethoxyphenethylamine fumarate
Chemical Class: Psychedelic phenethylamine
Molecular formula (fumarate salt): C12H19NO3 C4H4O4
Molecular mass: ± 325.34 g/mol
Appearance: White to light yellow powder (crystalline)
Purity: ≥ 98% (tested via HPLC & NMR)
Synonyms: Escaline hemi-fumarate, 4-ethoxy-mescaline

🧬 What is Escaline Fumarate?

Escaline is a psychedelic phenethylamine and a structural analogue of mescaline, with a ethoxy group instead of a methoxy at the 4-position. The fumarate version (salt form) offers improved stability and solubility, ideal for precise laboratory analysis.

⚠️ For analytical and pharmacological research only. Not for human consumption.

🔬 Applications in Research

Escaline is being investigated for his agonistic effect on serotonergic receptors (especially 5-HT2A), and its structural similarity to classical psychedelics.

Possible applications:

  • Receptor binding studies in serotonergic pathways
  • Neurochemical comparative study with mescaline, proscaline and isoproscaline
  • Pharmacokinetic simulations and SAR (structure-activity relationship) analyses
  • In vitro consciousness modeling via cell lines and receptor analysis methods

🧪 Use and Laboratory Instructions

  • Solubility: Freely soluble in ethanol, DMSO; moderately soluble in water
  • Recommended concentration (in vitro): 5–30 µM depending on assay type
  • Save: Dry, airtight and at 2–8 °C
  • Form: Hemi-fumarate (1:0.5 ratio Escaline:fumarate)
  • PPE recommended: Gloves, goggles, working under draught extraction

❌ Disadvantages and Risks

Although Escaline is valuable for scientific research, there are some limitations:

  • Limited research: Very little peer-reviewed data available
  • Psychoactive profile: Possible strong effect in case of accidental exposure
  • Legislation: Possibly illegal under analogue legislation (NL/BE/EU)
  • Structure sensitivity: Small molecular changes can dramatically alter biological responses

📊 Sample Laboratory Analysis

Batch code: ESC-FUM-2025-07
Tested by: DeltaChem Scientifics BV
Date analysis: 2025-06-10

Analysis methodResult
HPLC98.6% purity
NMR spectroscopyIdentity confirmed
FTIRFunctional groups according to
GC-MSNo impurities detected
Heavy metalsNot detectable (<0.01%)

❓ Frequently Asked Questions (FAQ)

What exactly does Escaline do?

Escaline is probably a 5-HT2A agonist, like mescaline, resulting in changes in perception and consciousness. However, the exact pharmacodynamics are still incompletely studied.

Is Escaline legal in the Netherlands?

Possibly not. Although it is often not specifically mentioned, it can be analogue legislation fall. Legal advice is recommended.

Is Escaline the same as mescaline?

No. It is an analogue: Escaline contains a ethoxy group instead of the 4-methoxy group of mescaline, which affects potency and binding profile.

Can I test or experience Escaline myself?

No. This product is intended for use only professional laboratory use and is not approved for human consumption.

Why is it supplied as fumarate?

The fumarate form offers:

  • Better chemical stability
  • Less hygroscopic behaviour
  • Simpler dosage management in research environments

⚠️ Legal and Safety Disclaimer

Not for consumption. Available only to academic institutions, research facilities and accredited laboratories. Sale to minors is prohibited. Manufacturer and seller assume no liability for misuse.