2F DCK HCl (2-Fluorodeschloroketamine Hydrochloride) – Scientific Product Description
General Features
2F DCK HCl is a fluorinated analogue of ketamine optimized for neuropharmacological research. This compound is being investigated for its potential as an NMDA receptor modulator, and provides insight into how halogenation affects pharmacological properties. Intended for use in professional laboratory environments only.Iboga root bark
Chemical Specifications
- IUPAC name: 2-(2-Fluorophenyl)-2-(methylamino)cyclohexanone hydrochloride
- Molecular formula: C₁₃H₁₇ClFNO
- Molecular mass: 257.73 g/mol
- CAS number: Not publicly registered
- Purity: ≥99% (HPLC-UV confirmed)
- Appearance: White crystalline powder
- Solubility: 87 mg/mL in water at 25°C
Scientific Applications
- NMDA receptor interaction studies
- Analysis of neuroplastic potential
- Investigation of halogen influences on receptor activity
- Comparative pharmacokinetics versus ketamine and analogues
- Metabolite identification and profiling
Safety Protocol
- Personal protection:
- Chemical resistant overall (Type 4)
- Double nitrile gloves (≥0.12 mm)
- Combination safety glasses and respirator
- Working environment:
- Negative pressure isolation cabin required
- Air monitoring active in powder processing
- Specific first aid and antidote facilities available
Storage and Stability Parameters 2F DCK HCl
- Long term storage: -80°C, vacuum packed
- Short term storage: -20°C under argon
- Photosensitivity: Class Ib (amber glass recommended)
- Humidity control: <20% RH with molecular sieves
- Stability:
- 24 months at -80°C
- 3 months at -20°C
- 72 hours at 4°C
Quality assurance
- Chromatography:
- UPLC-PDA for purity
- GC-MS for identity
- HILIC-MS for polarity verification
- Crystallography: PXRD analysis
- Elemental analysis: CHNS-O profile
- Isotope analysis: IRMS for origin determination
- Residual solvents: HS-GC analysis
Available Research Formats
- 250 mg (preclinical use)
- 1 g (full pharmacological characterization)
- 5 g (SAR studies)
- 10 g (large-scale applications)
Analytical Documentation
- UV/VIS spectrum (200–400 nm)
- FT-IR spectrum (400–4000 cm⁻¹)
- ¹H and ¹³C NMR (500 MHz)
- Mass spectrum (EI/ESI)
- Stability report in accordance with ICH Q1A(R2)
- Solubility profile in biological buffers
- Particle size analysis (via SEM)
Regulatory Framework
- Only allowed for in vitro and ex vivo research
- Not intended for diagnostic, human or veterinary use
- Local and international legislation must be strictly followed
- May be subject to export controls (WA list)
- Mandatory institutional approval for research application
Research support 2F DCK HCl
- Advice for receptor binding experiments
- Evaluation of compatibility with animal models
- Metabolite identification and analysis
- Structural modeling aid
- Pharmacokinetic predictions across multiple species
Scientific Relevance
2F-DCK HCl offers unique insights into:
- Fluorine substitution effects on NMDA receptor selectivity
- Penetration through the blood-brain barrier
- Comparative pharmacokinetics with ketamine and relatives
- Metabolic stability within human and animal models. Caluanie Muelear Oxidize
Our batches are manufactured under controlled cGMP-like conditions with full traceability and pharmacopoeial specification analysis, to ensure reliable results for neuropharmacological and analytical research.1cP-LSD 150 MCG Art Blotters